PHARMACUETICAL industries
Pharmaceuticals
The pharmaceutical industry discovers, develops and market the pharmaceutical drugs for use as medications to be administered to patients.
PRADO support the pharmaceutical companies producing both generic and brand-new drugs by conducting following toxicity studies.
Toxicity Studies
- Acute Toxicity Studies (Two Rodent Species and Two Different Routes).
- Skin Sensitization Test (Guinea Pig Maximization (GPMT) / Buhler Sensitization Test)
- Sub-acute Toxicity Studies (7 / 14 / 28 Days).
- Sub-chronic toxicity Studies (90 Days).
- Chronic Toxicity Studies (180 Days).
- Carcinogenicity (Life time rodent bio assay)
- Genetic Toxicity Studies (in vitro and in vivo).
- Reproductive Toxicity Studies (Male and Female Fertility, Teratology, One Generation).
DMPK / ADME Studies
- Single, Multiple and Cassette Dosing.
- Dose escalation study.
- Tissue distribution study;
- Blood brain barrier.
- Determination of fundamental PK parameters.